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Allertec Cetirizine is an over-the-counter antihistamine used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and itching caused by hay fever or other allergic reactions. The active ingredient, cetirizine, works by blocking the effects of histamine, a substance in the body that causes allergic symptoms. It can also be used to treat symptoms of urticaria (hives), such as itching and skin rashes.